A photo of Punam Malik.

Punam Malik, MD

  • Director, Cincinnati Comprehensive Sickle Cell Center
  • Program Leader, Hematology and Gene Therapy Program
  • Marjory J. Johnson Chair, Gene and Cell Therapy
  • Professor, UC Department of Pediatrics
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About

MBBS: University of Delhi, New Delhi, India, 1985.

MD: University of Delhi, New Delhi, India, 1989.

MS: University of Maryland, Baltimore, MD, 1991.

Fellowship: Children's Hospital Los Angeles, University of Southern California, 1995.

Services and Specialties

Research Areas

Insurance Information

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Publications

Preclinical efficacy of a modified gamma-globin lentivirus gene therapy in Berkeley sickle cell anemia mice and human xenograft models. Shrestha, A; Pillis, DM; Felker, S; Chi, M; Wagner, K; Gbotosho, OT; Sieling, J; Shadid, M; Malik, P. Molecular Therapy-Methods & Clinical Development. 2025; 33:101439.

An engineered β-globin homology donor reveals insights into β-globin expression and betters HDR. Chi, M; Malik, P. Molecular Therapy. 2025; 33:1308-1309.

Gene Therapy with Reduced-Intensity Conditioning for Sickle Cell Disease. Davies, SM; Grimley, MS; Shrestha, A; Shova, A; Asnani, M; Kent, M; Sayani, F; Quinn, CT; Niss, O; Lutzko, CM; Witting, S; Latham, T; Bushman, FD; Malik, P. Transplantation and Cellular Therapy. 2025; 31:s2-s3.

Underutilization of Disease-Modifying Therapies in Sickle Cell Disease: A Real-World Analysis from the ASH Research Collaborative Data Hub. Niss, O; Fenchel, M; Kingsley, E; Latham, TS; Malik, P; Quinn, CT. Blood. 2024; 144:2312.

Blockade of Angiotensin II Signaling Ameliorates Cardiac Fibrosis and Improves Diastolic Dysfunction in Mice with Sickle Cell Anemia. Little, K; Zhu, Z; Gbotosho, O; Malik, P. Blood. 2024; 144:2480.

Splenic Ossification in Sickle Cell Anemia Mice. Chi, M; Vandenheuvel, K; Malik, P. Blood. 2024; 144:5283.

A Novel Mouse Model of Hemoglobin-SC Disease: Bridging the Knowledge Gap in Sickle Cell Disease. Setayesh, T; Chi, M; Oestreicher, Z; Sakabe, M; Mei, X; Vandenheuvel, K; Townes, TM; Hu, Y; Malik, P. Blood. 2024; 144:620.

Longitudinal Assessment of Myocardial Fibrosis in Sickle Cell Disease. Niss, O; Morin, C; Lang, SM; Alsaied, T; Tasset, M; Malik, P; Quinn, CT. Blood. 2024; 144:799.

Preclinical safety assessment of modified gamma globin lentiviral vector-mediated autologous hematopoietic stem cell gene therapy for hemoglobinopathies. Shadid, M; Shrestha, A; Malik, P. PloS one. 2024; 19:e0306719.

NRASQ61R mutation drives elevated angiopoietin-2 expression in human endothelial cells and a genetic mouse model. Pastura, P; McDaniel, CG; Alharbi, S; Fox, D; Coleman, B; Malik, P; Adams, DM; Le Cras, TD. Pediatric Blood and Cancer. 2024; 71:e31032.

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